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These cases highlight the importance of comprehensive evaluation of new brain lesions in patients with nonmetastatic solid tumors. Characteristics of new brain lesions in patients with cancer that should raise suspicion of diagnoses other than brain metastasis include (1) primary malignancy without regional or distance metastasis (2) imaging without discrete mass-like enhancement, and (3) cortically based location of lesions not at the gray-white matter junction. |
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